Many topical products, including emollients, contain excipients in addition to the active ingredient(s). These excipients have various useful roles:
- Thickening agents – to thicken the product.
- Emulsifiers – an emulsifier allows oil and water to mix and, by reducing the surface tension, has a stabilising effect on the emulsion.
- Preservatives – prevent microbial spoilage of the product by killing off or inhibiting the growth of micro-organisms.
- Buffers – maintain the pH environment of the product throughout its shelf life.
- Fragrances – provide a distinctive odour to the product which can be used to mask the smell of unpleasant ingredients within the product.
However, certain excipients are known irritants and / or sensitisers. Such excipients can aggravate already sensitive skin causing reactions that result in the development of skin inflammation and itchiness. This would result in your patient scratching causing further damage, exacerbating the itch-scratch cycle and preventing the skin from repairing itself. Symptoms typically seen include skin which can be red, swollen, blistered, dry, thickened, intensely itchy and cracked depending on whether the reaction is acute or chronic2. The two conditions, allergic and irritant dermatitis, may co-exist.
This is why the complete AproDerm® Range has been developed to be free from the following common irritants and sensitisers:
Hence it can be considered that the risk of a reaction to a patient will be greatly reduced thus aiding compliance. To find out more about the common irritants and sensitisers that the AproDerm® Range is free from click on the relevant box below: